Of all the problems which were open to me for study, typhus was the most urgent and the most unexplored. We knew nothing of the way in which contagion spread.
Charles Jules Henry Nicole
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I finally demonstrated that typhus infection is not hereditary in the louse.
- Charles Jules Henry Nicole -
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The discovery that I soon made that the guinea pig was also susceptible to infection made it possible for me, from the third year on, to preserve the virus on this animal.
- Charles Jules Henry Nicole