Most of the doctors in the Tunisian administration, especially those in country districts, contracted typhus and approximately one third of them died of it.
Charles Jules Henry Nicole
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The discovery that I soon made that the guinea pig was also susceptible to infection made it possible for me, from the third year on, to preserve the virus on this animal.
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Just as the only reservoir for the typhus virus in nature is provided by man, so the only vector of infection is the louse. The bite of the louse is not virulent immediately after the infecting meal. It becomes so only towards the 7th day following infection.
- Charles Jules Henry Nicole