(showing 1-10 of 20)
If, for example, all the codons are triplets, then in addition to the correct reading of the message, there are two incorrect readings which we shall obtain if we do not start the grouping into sets of three at the right place. Francis Crick#Uncategorized 64
Francis Crick#Uncategorized 64
It now seems very likely that many of the 64 triplets, possibly most of them, may code one amino acid or another, and that in general several distinct triplets may code one amino acid. Francis Crick#Uncategorized 58
Francis Crick#Uncategorized 58
If the code does indeed have some logical foundation then it is legitimate to consider all the evidence, both good and bad, in any attempt to deduce it. Francis Crick#Uncategorized 58
Do codons overlap? In other words, as we read along the genetic message do we find a base which is a member of two or more codons? It now seems fairly certain that codons do not overlap. Francis Crick#Uncategorized 46
Francis Crick#Uncategorized 46
A comparison between the triplets tentatively deduced by these methods with the changes in amino acid sequence produced by mutation shows a fair measure of agreement. Francis Crick#Uncategorized 28
Francis Crick#Uncategorized 28
It is essential to understand our brains in some detail if we are to assess correctly our place in this vast and complicated universe we see all around us. Francis Crick#Universe 26
Francis Crick#Universe 26
How is the base sequence, divided into codons? There is nothing in the backbone of the nucleic acid, which is perfectly regular, to show us how to group the bases into codons. Francis Crick#Uncategorized 25
Francis Crick#Uncategorized 25
The meaning of this observation is unclear, but it raises the unfortunate possibility of ambiguous triplets; that is, triplets which may code more than one amino acid. However one would certainly expect such triplets to be in a minority. Francis Crick#Uncategorized 25
It seems likely that most if not all the genetic information in any organism is carried by nucleic acid – usually by DNA, although cetain small viruses use RNA as their genetic material. Francis Crick#Uncategorized 25
It is one of the more striking generalizations of biochemistry – which surprisingly is hardly ever mentioned in the biochemical textbooks – that the twenty amino acids and the four bases, are, with minor reservations, the same throughout Nature. Francis Crick#Nature 24
Francis Crick#Nature 24
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