Despite the old adage, everyone judges your book by its cover - including the title, so they need to not only be eye-catching, but also convey the tone and genre of the book. I believe it's important to be aware of trends in your genre but not to be limited by them. There won't be a new trend until someone steps out and goes in a new direction.
I work mostly in crime fiction, but I have written in other genres: sci-fi, adventure, fantasy, historical fiction and drama. I don't know if I could pick just one :(
I actually have done this. My first book was published in 2013, and I thought I was happy with it. But five years later, I realized the opportunities I had missed for making the book so much better. So, I pulled the original from publication, made the changes, and re-released it as the 5th Anniversary Revised Edition. I am so glad I took the chance, especially since I've sold more copies of the new edition than I ever did of the original :)
For me, the best way to combat writer's block or when the inspiration seems to dry up is to move on to a different project. I keep a minimum of three WIPs going at once so I can rotate through them. When I hit a wall in one, I work on number two until I get stuck there, then number three, etc. Usually, by the time I rotate back to number one, it has percolated and simmered in the back of mind long enough for a solution to the issue I was having to present itself.
